In Route, three orphaned sisters endure a tumultuous car ride on California's i280 after an explosive sex scandal at their Catholic school involving the middle sister, Jade. Sole guardian and eldest sister Scarlet attempts to uncover the true reason why Jade would flippantly throw away her future, all while hiding a scandalous secret of her own. While trying to keep the peace, nine-year-old sister Georgia discovers much more than she bargained for about the sisters she thought she knew.
